In a small bowl melt butter in the microwave, add to the melted butter the following: Worchestershire sauce, onion powder, and garlic powder. Stir well.
Pour the cereal, pretzels, and nuts onto a rimmed baking sheet. Drizzle over seasoned butter sauce. Mix well.
Place the pan into the heated oven, stir every 15 minutes for 45 minutes. Then remove pan.
Allow the mixture to cool to room temperature before storing it in an airtight container.